What is Sepsis?
Blood Stream Infection
Sepsis, also referred to as blood poisoning or septicaemia, is the body’s life-threatening immune response to infection (bacteremia or other infection). Usually, the body’s response to infection is localized to the specific infection area. But in sepsis, a systematic response to infection occurs throughout the body which can cause organ failure and life-threateningly low blood pressure.
Sepsis can claim lives within hours.
Need for Rapid Diagnosis
People with sepsis are usually treated in hospital intensive care units. Doctors try to quell the infection, sustain the vital organs and prevent a drop in blood pressure. The first step is often treatment with broad-spectrum antibiotics, medicines that kill many types of bacteria.
Current clinical practices (pathogen culture and PCR amplification) can take as long as 48 hours to sensitively detect sepsis. Clinicians are urgently looking for a rapid and sensitive alternative to combat rising sepsis incidence, healthcare costs, and antibiotic-resistant superbugs.